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AS EXPLAINED previously, cancer is not a specific illness but a general, chronic, degenerative disease. To a certain extent, it may be due to the inheritance of a predisposing factor such as a weak liver but more frequently it is caused by outside influences which have come about by our way of life. A noted cancer biologist, Professor Little, expressed this thought as follows:
"Cancer develops where there is a general breakdown of the whole body."
Most scientists reject this and similar theories and continue to adhere to the conservative doctrine that cancer is a localized disease, at least in the beginning. They consider it a specific syndrome,114 despite the fact that they do not know the underlying cause. Later when it spreads over the body, it is called a generalized disease, but it is only secondary. Accordingly, the recognized treatments are local treatments - surgery, X-ray, radium, or chemical treatments by application of mustard gas, ionized phosphorus, iodine, cobalt,115 copper, or the administration of sex hormones. The chemical and hormone treatments are supplementary treatments only. Contrary to the opinions of the majority of the scientists, a number of pathologists feel that they can no longer maintain the doctrine of a local development of cancer. They, therefore, turn to a more general theory. To give a few examples of these new approaches, let us cite Professor Siegmund (translated):116
"The theory of cancer is a question of the defense of the mesenchym (connective tissue) especially a defense work of the whole organism against damages penetrated from outside or developed from inside. In the end, the therapy is a so-called parenteral digestion. Nutrition is originally an external factor but the organism acquires a disposition growing into premorbidity through constant intake of denaturalized food."
Professor Pischinger places the activation of the mesenchym more precisely into the foreground:117
"The mesenchym consists mostly of connective tissue cells which are distributed all over the body, especially between all organs and tissues. It contains some different types of cells. This tissue was long ignored until a few scientists discovered the importance of this so-called `filling tissue', now characterized more precisely as the `reticular system', containing the mesenchymal defense and parenteral digestive apparatus. From the pathology we learn that allmost every tumor is surrounded by such tissue, and the same tissue also embraces all new cancer establishments. This connective tissue is almost inactive and paralyzed in cancer, incapable of helping or protecting the body any longer in defense or healing."
A number of scientists have tried various methods to stimulate the reticular system as well as the reticulo-endothelial system, which seem to control and regulate the growth of cells. Failure of these systems may cause the uncontrolled growth, which is a characteristic part of cancer.
I have found that this important system cannot function sufficiently and satisfactorily because the entire body is poisoned and has lost part of the ionized minerals of the K-group and simultaneously some of the electrical potentials, etc. Many scientists regard these systems as part of the healing apparatus.118
Professor G. von Bergmann described this method of cancer development by writing (translated):
"Cancer metabolism takes place once the body is no longer capable of producing an active `inflammation metabolism' ... the cancerous organism is anergic in respect to inflammation."119
The experiments of his assistants, Ruth Lohmann and Peschel demonstrated, as reflected in the following tables, that cancer cells can be killed in fluid from a normal inflammation metabolism, not in blood serum. This indicates the fact a normal body can kill cancer by producing an inflammation.
| TABLE I115 | ||||
| Out of Serum | Out of Inflammation Fluid | |||
| I | QO2 | H−Q−O2 | QO2 | H−Q−O2 |
| 0 hours | 10,8 | 23,4 | 11,2 | 21,8 |
| 6 hours | 10,2 | 21,8 | 6,9 | 13,3 |
| 10 hours | 9,7 | 18,9 | 2,8 | 2,9 |
| 14 hours | 9,6 | 17,5 | 0,0 | 0,0 |
| II | QO2 | H−Q−O2 | QO2 | H−Q−O2 |
| 0 hours | 11,3 | 17,6 | 12,0 | 21,1 |
| 12 hours | 8,8 | 16,6 | 0,0 | 0,0 |
| 115 Op. cit., p. 174. | ||||
| Normal Serum | Inflammation Fluid | |
| Oxygen pressure | 117 mm Hg | 6 mm Hg |
| Sugar content | 100 mg % | 6 mg % |
| Lactic acid content | 10 mg % | 125 mg % |
| Bicarbonate content | 25 ·10−3 molar | 8,9 ·10−3 molar |
| pH | 7,48 | 6,29 |
The papers of Friedrich Kaufman on non-bacterial inflammation revealed that these inflammations are followed by mesenchymal inflammatory reactions of genuine nature, with capillary activity, cell activation and loss of white blood cells. In the same animals, changes in the liver were found at the same time, on the epithelian parenchym, in connection with the liver cells themselves as well as by inflammatory reactions on the mesenchymal tissue.
A few of my own experiments with cantharidin plasters have confirmed the fact that cancer patients could not produce an inflammatory reaction after irritation by cantharidin chemical. The only exception was a case of beginning skin carcinoma, which produced about a third of the normal reaction; but the blister fluid could no longer kill cancer cells. After several months or longer of detoxication, diet and medication, patients showing favorable response were able to produce a normal inflammation metabolism, capable of killing cancer cells. In this country, I was not in a position where I could carry out enough experiments to constitute a scientific proof of the fact that general detoxication and restoration of the metabolism are basic parts of the healing of cancer.
G. von Bergmann widens the conception of inflammation as an allergic reaction by writing: "The sicknesses which are in our doctrine of diseases separated according to the different organs have common biological reactions with cellular procedures surpassing the defense of the reticulo-endothelial apparatus. Included in the allergic reacting organs are: the diseases of the stomach as well as the colon, the great glandular parenchymatous organs of the liver, pancreas, meninges, endocard, pericard, synovia of the joints - finally the muscles, not the least being the heart muscle, in particular the vessels, the arterioles, venules as well as the capillaries - all of them reacting with invisible biological structural changes of the cells and tissues and in the `humural condition'."121
The theory of the functional part of the diseases von Bergmann calls "pathology of the function", which can lead in both directions either to the advantage or disadvantage of the organism.
Now we come to the core of the problem as to whether we can influence these biological or allergic reactions, and how far and in what manner one can direct them.
The cancerous body presents in general an "anergic reaction" as far as the cancer mass and its metabolic poisons are concerned. Therefore, in more advanced cases, light infections may be fatal. All attempts to stimulate the system by virulent skin infections or combinations of their toxins to an allergic response against the cancer consistently failed.
Later the unspecific allergic reactions became clinically more important symptoms regarding the progress of the doctrine of the inflammation. First von Pirquet and later Schick studied the internal inflammatory conditions more intensely.
It was found that the cantharidin blister fluid can be used as a measurement indicating the degree of inflammatory preparedness (called allergy) of the total body, its variability during the course of the infections and other noninfectious diseases, and, I would like to add, for the confirmation of the healing in chronic diseases and cancer although not enough experiments have been carried out to date.
The decisive step forward came when the Berlin pathologist, Professor Roessle, published his experiments. He showed that guinea pigs reacted with different types of white blood cells disappearing from the irritating capillaries by the same stimulus but after different kinds of previous treatments were applied to the animals in using injections of various protein solutions. On such a basis, more and more authors came to the conclusion that the body and its present state of inflammatory preparedness decide the degree and type of inflammatory-reaction, not the degree or type of the applied stimulus. Likewise, Virchow's cellular pathology is no longer valid in this respect, but the predominant functions of the cells and their changes are effective.
The same discovery was made in the field of tuberculosis by K. E. Ranke when he stated that not the virulence nor the amount of tuberculosis bacilli determine whether there will be an exudative or productive type of lung tuberculosis, but rather the character of the reaction of the organism against the stimulus is decisive. The reciprocal effect between reagens and reactor can be so great that any common virulent streptococcus stock, for example, can be changed to a weaker type such as streptococcus viridans which occurs in sepsis lenta (older observations).
To see the advantages of the allergic inflammation we have to look into the anatomical and biological findings of this function. This subject is described at length in my tuberculosis book,122 which also includes an explanation of the Arthus phenomenon in limiting the spot and saving the body.
We learn from pathological and experimental findings that in cancer there is no sufficient blockade around the tumor. The way is free for new settlements to spread and thus poison the body and keep it under its destructive rule. The degree of the barrier and the capacity of the elimination organs, particularly the liver, determine the progress of poisoning and breakdown of the body, while the defense apparatus becomes more and more inactive.
The fact that we regard the body in its entirety should not lead us to assume that the tumor, the glands and the metastases can be influenced at one time or even cured all together. The concept of totality should not let us forget that each sick organ, even each node and gland, has its own pathological anatomical conditions, on which the method of healing essentially depends. Osteolytic and osteoplastic processes can exist in the same organ or even in the same vertebra nearby and it appears that each single spot, node, tumor or destructive process has some biological laws; despite this, it remains the task of the treatment to subordinate all the pathological and healthy organs, tissues, and cells for the benefit of the whole. This is the natural way for the metabolism to be supported by the autonomous nervous system with the reticulo and reticulo-endothelial system. The close cooperation of the liver is essential.
Because of the continuous failures in the extensive experimental research, most of the authors are unsuccessful in solving the cancer problem. In my opinion, primarily because comprehension of the detoxication has always been overlooked in clinics, we are not sufficiently trained in that direction. In addition we have to take into account that we have very little or transient or symptomatic results in other chronic diseases. After such experiences, it is very difficult for the physician to accept the idea that a cancer patient can be completely restored. G. von Bergmann wrote: "A systematic therapeutic development of this theory may not be possible, ..."123 This means that he, as most other authors, never expected that it might be possible to restore metabolism in a cancerous organism to an extent sufficient for healing purposes.
I repeat: The cancerous body is anergic, which means that it cannot prevent cancerous growth nor respond and defend itself against it. The treatment, therefore, has the task of restoring these normal functions so that the defense apparatus, liver with reticulo and reticulo-endothelial system can function and that finally, the conditions are restored for production, activation and reactivation of oxidizing enzymes.
We have very often seen, in the more advanced cancer cases that there are only a few lymphocytes (on the average 3-10 in the so-called "differential count"). This shows that the body is no longer capable of producing the necessary amount of lymphocytes for its normal need or for its healing power. We see not only in cancer, but also in other chronic diseases, that the body has lost the activity of the valuable and necessary mother-tissue of lymphocytes. If we follow the suggestions of some authors, we may assume that the reticular and the reticulo-endothelial systems both are the terminals of the visceral nervous system. These authors also think that the functions of our internal organs depend, to a greater degree, on the functions of that autonomous system. Professor Pischinger reminds us in his article that these tissues also play a central role in the "budget of the oxygen", thus helping to bring oxygen into the cells. From Professor Schade's work we know that the connective tissue is interposed between the capillary and the epithelial cell, or any other cell, in the body. If we assume that the visceral nervous system, the reticulo-endothelial system, the interposed connective tissue and, on the other hand, the reactivation also of the oxidizing enzymes is more or less damaged in the cancer body, we may understand that some abnormal cells are forced to go over from the use of oxygen to the use of fermentation, which changes the life conditions of these cells and their growth and penetrates the surrounding tissue to the greatest degree.
In all experiments except for one which could not be confirmed, it was found that cancer cells cannot be stimulated or forced to change their abnormal functions back to normal ones. There is no other way but to kill these cells to dissolve and absorb them. I believe the surest way to achieve this end is to restore to the body its ability to produce non-bacterial inflammatory reactions. The idea of producing bacterial inflammations in a cancerous body was correct in principle. However, it is not enough to introduce a temporary inflammation into the body. The body itself must be able to do it and do it continuously, because many cancer cells remain hidden in some areas where even the blood stream cannot reach them. In order to maintain this healing process, it is, of course, necessary to apply the treatment long enough to restore all vital organs to normal function (liver, reticular system, nervous system, etc.) to reproduce the same reactive processes as used by the body itself, for healing purposes.
From observation of the skin, I could learn what types of proteins and fats are favorable, at what time the reserves of the tissues must be refilled, and what is necessary to produce the best healing reactions and, finally, how to keep them at the level necessary for healing purposes. For these tests, therefore, we had to select cases which had skin cancer, or, better still, such cases which had internal cancers and skin eruptions of acute or chronic nature, or cancers with additional skin metastases or additional skin cancers. It may be generally concluded that cream, fatty cheese, all animal fats, some oils, egg yolks, strawberries, and all fat varieties of meats indicated their harmfulness on the skin, probably because they were only partially digested, whereas lean meats, fresh butter and some different types of oil were not harmful.
In all cases where the metabolism was above plus 25 per cent, almost all proteins and fats were unfavorable. In cases where the metabolism was minus 10 per cent and lower, all fats and oils were harmful, whereas lean meat and egg whites were so to a lesser degree. In quite advanced cases there was no time for such examinations as the treatment had to be applied immediately and most intensely. In a few such cases the content of cholesterol in the blood was greatly increased, while trypsin and lipase were almost lacking. The milder cases had less cholesterol and at least some trypsin and lipase content. Almost all cancer cases showed an acceleration of the healing processes when thyroid and lugol solution drops were increased, while hormone therapy was generally harmful in the beginning. Where there was hardening of the arteries, thyroid and lugol were especially favorable. Also in such cases where we could not verify the improvement on the reactions of the skin, longer, intensive and more frequent treatments with iodine (thyroid plus lugol) and potassium compound were required.
It is our assumption that every defense and healing power of the body depends on the capacity of the body to produce a so-called "allergic inflammation".124 Every healing is introduced by a kind of inflammation as we learn in surgery. It is also true in medicine. All different types of foreign bodies, such as bacteria and injuries, have the capacity to bring about such a healing inflammation in a healthy body. It presents an afflux of blood with redness and swelling. The redness is caused by the opening of the capillaries and some special cells. The fluid of the swelling is not identical with edema fluid; it is a product of hyperemia and inflammation; it is an extravasate through finely damaged capillaries. The different kinds of fluid in edema and inflammation are not yet fully known. Otto Warburg demonstrated that the cancer cell has good living conditions in blood serum and in the inflammation fluid these conditions are lacking, for this fluid is composed in such a way that the cancer cell will not find enough sugar in it for glycolysis. Warburg showed that when the sugar level sinks to 20 mg. per cent, the lactic acid production falls to half and that the low level is lowered still further in the inflammation. In chronic or degenerative diseases such as tuberculosis, arthritis, arteriosclerosis, etc., the body has lost the capacity to bring about such an "inflammation reaction".
In cancer some authors125 say where the body has been sick before, cancer could develop. G. von Bergmann explains the impossibility to prevent or cure cancer: "Cancer sets in where the body is incapable to produce an active inflammatory metabolism". (p. 178.) Strong denies (1940) that "up to the present there is not yet one cancer attacking defense mechanism revealed". Dr. L. Alibert and several students (1808) were inoculated with cancerous material from a female breast tumor. It produced violent inflammatory reactions. Then Emil Weiss of the Peoples Hospital, Department of Pathology, Chicago, inoculated an extract of human cancer into patients affected with cancer. The aim of that clinical trial was to find what therapeutic effect such treatments have. After injections, chill and temperature lasted for two hours and more. The results were a marked increase in appetite, more strength, and a slight increase in weight. The lymph nodes diminished and became much harder. No cure was obtained - only temporary improvement.
Dr. Fehleisen (1883, Berlin Charité) inoculated real erysipelas infection into cancerous areas. This resulted in many failures and a few remarkable successes. G. von Bergmann thinks that every experienced clinician knows of a few carcinomas cured by intervening inflammatory processes.
Dr. William B. Coley, New York (1891), devoted his life to this dramatic treatment with erysipelas inoculations, later with pyogenic mixtures such as streptococcus, staphylococcus and pyocyaneus, still later adding bacillus prodigiosus. Coley's results and those of others remained quite uncertain and sparing. The great majority of the medical profession remained very skeptical about this method of cancer treatment.
The idea of helping the cancerous organism through a strong inflammation is old but was correct from the beginning. The problem is to find the surest and most effective way to do this.
Cancer patients have different types of allergic reactions. Some patients with Hodgkin's disease responded with alcohol-induced pain due to malignancy.126 The pain was regarded as an allergic reaction brought about by a carcinoma, as it was not present before the disease. The patient had apparently enough power for an allergic reaction but not enough for an "allergic inflammation" - not intensive and active enough for an "allergic inflammation" which is the decisive part of the body's "weapon of healing power". Consequently, it appears that there must be a characteristic difference between allergic reactions and allergic inflammations, since both are not quite separated in their limitation and causation. At the beginning of the cancer we can assume that with the allergic reaction there is still a part of an allergic inflammation present and effective, too weak, of course, for healing power, but to a certain degree sufficient to restrict the tumor and to keep it temporarily localized. It is reported in the same article that the patient with allergic reaction to alcohol (20 ml.) had only a slight discomfort caused by the allergic reaction to alcohol when the roentgenogram showed that the tumor was larger and better defined. Later, the "anergia" increased when the tumor grew faster, and there was no longer pain after drinking the quadruple amount of gin (80 ml.). Such observation indicates most probably that the increase of intoxication decreases gradually the allergic reaction to nil. These and other observations are significant signs of the reduction of allergic reactions by progressing intoxication imminent in a cancerous body. It therefore appears that the body's capacity to produce an allergic inflammation (healing power) depends on a most complete detoxication and an equilibrium in the metabolism to near normal.
The healing apparatus seems to have retained part of its embryonic capacity and healing purpose for a type of regeneration,127 when it falls back into the embryonic state temporarily and is activated above the degree of its normal function.
The completely detoxified body is then able to produce an allergic inflammation if the healing apparatus (liver, visceral nervous system and reticulo-mesenchymal system) can be activated sufficiently. Everything that can help to bring it about and strengthen the necessary allergic inflammation may be used for that purpose after the general detoxication has taken place. Bacterial preparations (Coley and others) or Pyrifer, or any similar preparations are effective, as far as they can stimulate the visceral nervous system in connection with the liver and the mesenchymal defense and healing apparatus. We have to bear in mind that there are very different reactions according to the state and energy-capacity of the healing apparatus. It may be advisable to stimulate, in addition to my treatment, the liberated visceral nervous system and the reticulo-endothelial apparatus with a measured bacterial reagens. However, I have had no experience with it. We do not know what stimulus acts first and what tissue should be activated. G. von Bergmann (p. 171) quotes the description of the course of the inflammation from an article by Kempner (translated):
"At any stimulus an exudation and immigration of white blood cells sets in. The chemical composition of the exudate is the same as that of the serum (in the beginning). As soon as the exudate and the inflammatory cells are present, there starts an own life separated from normal tissue within the inflammation area, in the center of which is the metabolism of the inflammatory cells. The velocity of the inflammatory reactions depends upon the presence of inflammation cells. These cells have an oxidative and digestive metabolism and by means of this metabolism cause an acidosis of the inflamed tissue and reduction of the inflamed space of oxygen and energy-producing substance (sugar). Acid formation and deficit of energy-producing substance bring about damage or destruction of inflamed tissue, a kind of swelling, degeneration and necrosis."128
After the inflammation has killed the tumor mass, (See Tables I and II, this chapter) necrosis sets in. In necrosis of circumscribed localized areas the important function is the digestive power of leukocytic enzymes of fibrin and debris in inflamed areas, for indigested fibrin acts as a foreign body and leads to fibrosis. "The term necrosis is used to describe the changes which the dead tissue and cells undergo after their death. The term necrobiosis is used in reference to the physiologic death and replacement of certain cells which are constantly occurring, e.g., blood cells and in epidermis."129
My own observations have shown that far advanced cancer patients have lost their allergic migraine reaction and other kinds of allergic reactions. During the healing time the migraine symptoms recur partially but disappear when the patient is cured entirely, as the combined dietary regime is enough to cure allergic migraine symptoms in most cases without combination with cancer; I also made similar observations with other allergic manifestations. In all these instances it was found that the degree of allergic reactions varies inversely with the degree and period of shorter or longer lasting intoxications. Cancer patients with allergic syndromes are forced to maintain part of the diet without salt and with low animal fats and proteins for many years.
I do not believe that there is fundamentally more than one healing apparatus in the body. Strong said (1940): "Up to the present there is not yet one cancer attacking defense-mechanism revealed."
The treatment is, of course, unspecific. To reject any dietary regime because of insufficient physiological proof is not sound.130
On the skin where we had been able to study the healing of lupus (see my Tuberculosis book, p. 200) we could also observe the following in cancer: After the body is detoxified, inflammation with redness and slight swelling of the involved spot starts. A few days later the reduction of the edema and infiltration sets in. The abnormal spot and the secondary infections will be dissolved by the digestive enzymes and finally absorbed into the blood stream. Under the microscope, we see the creation of new capillaries which penetrate into the infiltrate and the necrotic mass and build the so-called granulation tissue.
They secrete all different hormones and probably also enzymes, similar to the placenta tissue in cooperation with the oxidation processes (it is the function of leukocytes, lymphocytes, histiocytes). The healing process starts with hyperemia and then the different stages of reabsorption follow. The blood pictures show at that time an increase in leukocytes and lymphocytes and a small increase in monocytes. During the healing time a small increase in lipase was confirmed, a necessary development for the digestion of the fatty cell fragments. At the beginning of the dietary regime, we saw and learned that some nutrients hinder the healing process, whereas others further it. These observations were used as indicators to point out what substances damage or which other ones are necessary for the healing process in that period.
Despite the observation that we can see the healing processes in skin cancer under the microscope, the fact remains that we do not know exactly the organ or organs which have to be stimulated and we do not know what part of the treatment activates them.
We do know that a healing apparatus is present and functions in a healthy body - and we learned, in addition, by means of this treatment that it can be reactivated if the body can be sufficiently detoxified (in degenerative diseases and cancer).
We have the distinct impression that the internal organs present similar or equal situations under treatment which the skin cancer reflects. The X-rays prove it on the bones, lungs and other organs.
Deep reaching cancerous ulcerations need several corresponding inflammations (so-called "flare-ups") until the larger area is covered with more granulation tissue or new skin.
These "flare-ups" come at intervals and with some women just before their menstruation.
My idea is that the detoxication obtained by frequent enemas, by the dietary regime and some medication pave the way for the first allergic healing inflammation; the body must be maintained detoxified and in a metabolic equilibrium even with a partially functioning liver for the following "flare-ups".
We should not forget that after the killing of the tumor mass and its dissolution, the absorption, until recovery is a constant heavy burden on the elimination apparatus, in particular on the liver and kidneys. If we do not help the patient intensively day and night to eliminate these additional poisonous substances, as I have seen it at the beginning of this treatment, there is a serious danger that the patient may fall into a hepatic coma.
In the first two weeks of this treatment we observe that the patient awakes from the half comatous mood, caused partly by a previous high sedation therapy and partly by the toxins from the growing tumor masses accumulated and now activated in the body. In the first ten days the urine shows much elimination of NaCl, up to eight grams per day, rarely ten grams. Acetone plus two to three, disappears in about one week, often together with a trace of albumin and hyaline casts.
The red blood picture recovers steadily in four to six weeks; the white differential count shows that its production apparatus has to carry the burden.
Within a few days all white cells have toxic granules, the lymphocytes increase slowly, the number of leukocytes remains increased for a few weeks also the percentage of neutrophiles. We learned that the stronger the detoxication, the quicker and more surprising are the results, as long as we are able to keep the metabolism free of poison and equalized in many respects despite the fact that we have to handle other heavily damaged or even partly destroyed organs.
In this way it is possible to bring the cancer-mass or masses out of their partial seclusions or hiding places back into the exchange of the general metabolism, into its support and regulation. However, the detoxication is only a part of the healing process though an important part. Simultaneously, the metabolism has to be balanced at least to a certain degree. The sick organs are unable to do so themselves for a long period, especially in advanced cases.
The body needs essentially: the important minerals (K, I, P), the oxidizing enzymes and coenzymes, and the hormones.
All of them must become activated in the body and must be re-activated there, otherwise they are lost. Equally important is the restoration of the pH (minerals in the cells) so that the enzymes can function again step by step.
All the explanations in this book about the healing of cancer as well as other presentations would be not much more than words, if we were not able to demonstrate the corresponding clinical facts of real healings. But after these facts are achieved, these conceptions are explanations for our clinical observations.
Our modern civilization has brought about such widespread changes in our nutrition that some cancer authors speak about a so-called pre-cancerous condition. I feel it must be expressed more generally as a pre-morbid pathology. For our task it is important to know that we have no longer a natural nutrition; therefore, the therapy is more difficult. The pre-stages probably could be recognized by examination of K, I, urea-N and uric acid, and could be more easily restored. The cancerous tissues, however, must be killed, since after their microsomata and mitochondria took in certain biochemical changes in minerals and electrical potentials and probably also particles of a new protein substance into their cell formation, they cannot be retransformed to normal.
Finally, healing of cancer means the restoration of the entire metabolism with its enteral and parenteral digestion together with its defense and healing functions.
Extirpation of cancer growths does not mean a cure of the disease. The improvement which frequently follows an operation may show that the liberation of the body from such poison-producing mass is a great help for the system, and points to the direction that the partial detoxication of the body benefits the cancer-hearing system at least to a certain degree, and temporarily. The improvement seems to be only in the beginning, after the operation and in localized cases only, but this is not sufficient for the production of an allergic inflammation. In the literature, the allergic or healing inflammation is referred to as "changes in the environmental conditions." This is an incorrect conception.